PicoSure & Synergy Multiplex Laser

Dual-Targeted Pigment Shattering & Vascular Microenvironment Control

Complex Asian and international pigmentary disorders—such as mixed dermal melasma, solar lentigines, post-inflammatory hyperpigmentation (PIH), and post-acne erythema (PIE)—rarely exist in isolation. Chronic dermal inflammation and abnormal micro-vessels continuously feed melanocytes via Vascular Endothelial Growth Factor (VEGF). At Jenny Clinic, Board-Certified Dermatologist Dr. JayU Choi and Representative Director Dr. Minjung Cho lead a precision multi-wavelength laser protocol combining Cynosure PicoSure, Synergy Multiplex, and Clarity II.

Cynosure PicoSure (755nm Alexandrite Picosecond Laser)

• Selective 755nm Melanin Absorption: Unlike standard 1064nm lasers that show significant competing absorption in hemoglobin, the FDA-cleared 755nm Alexandrite wavelength of Cynosure PicoSure offers three times higher selectivity for melanin over blood—minimizing pinpoint petechiae and surrounding thermal injury.
• Focus Lens Array & Laser-Induced Optical Breakdown (LIOB): The diffractive Focus Lens Array concentrates picosecond acoustic energy into microscopic high-fluence zones, generating intra-epidermal Laser-Induced Optical Breakdown (LIOB) vacuoles. This photo-mechanical pressure wave shatters stubborn melanin granules into dust-like particles for rapid lymphatic clearance while stimulating dermal collagen and elastin remodeling—without triggering thermal rebound melasma.

Synergy Multiplex (Sequential 585nm PDL + 1064nm Nd:YAG) & Clarity II

• Synergy Multiplex Vascular Laser: Emits sequential 585nm Pulsed Dye Laser (PDL) and 1064nm long-pulsed Nd:YAG pulses through a single handpiece. The 585nm pulse converts oxyhemoglobin into methemoglobin, increasing absorption of the subsequent 1064nm pulse by up to 300%. This allows lower, safer fluences to coagulate abnormal dermal telangiectasia, resolve VEGF-driven vascular melasma, clear red post-acne marks (PIE), and calm rosacea flushing.
• Lutronic Clarity II (Dual 755nm Alexandrite & 1064nm Nd:YAG): Features Intelligent Capabilities and real-time temperature sensing with cryogen cooling to address discrete epidermal freckles, lentigines, dull skin tone, and diffuse facial redness.

Clinical Protocol & Treatment Specifications

Clinical Parameter	Specification
Laser Platforms	Cynosure PicoSure (755nm Picosecond + Focus Lens) + Synergy Multiplex (585nm/1064nm) + Clarity II
Core Mechanism	Photo-mechanical LIOB melanin shattering + sequential dual-wavelength vascular coagulation
Target Indications	Melasma, vascular melasma, solar lentigines, freckles, PIH, post-acne erythema (PIE), rosacea, pores
Lead Physicians	Board-Certified Dermatologist Dr. JayU Choi & Representative Director Dr. Minjung Cho
Procedure Duration	30 to 50 minutes (including diagnostic skin analysis and post-laser cryo-soothing)
Anesthesia & Cooling	Topical anesthetic cream (when indicated) + integrated Zimmer air cooling / dynamic cryogen spray
Downtime & Recovery	Minimal downtime; mild transient pinkness for 3 to 24 hours; subtle micro-crusting on discrete spots
Complementary Care	Pairs with Rejuran Healer & Skin Boosters for dermal barrier strengthening

Why Treat Melanin and Micro-Vessels Simultaneously?

1. Preventing Rebound Melasma: Aggressive high-heat laser toning alone often aggravates underlying dermal capillaries. Pairing PicoSure photo-acoustic toning with Synergy Multiplex vascular stabilization targets both the pigment and its vascular feeder network.
2. Simultaneous Acne Redness (PIE) & Brown Marks (PIH) Clearance: Resolves persistent red vascular macules and brown post-inflammatory pigment in a coordinated session.
3. Pore & Texture Refinement via LIOB: PicoSure Focus Lens pressure waves stimulate new dermal collagen without ablative downtime.

Discover our complete Pigmentation & Brightening Lasers department or explore peer-reviewed dermatological studies on 755nm picosecond LIOB and dual-wavelength vascular lasers via PubMed (NCBI) and melasma care guidelines from the American Academy of Dermatology (AAD).

Reserve Your 1:1 Dermatology Laser Consultation

Every pigment lesion requires accurate differentiation between epidermal, dermal, and vascular components before selecting wavelength and fluence. Contact our international concierge team via 1:1 Consultation Inquiry, Official LINE (@853akazy), or Official WhatsApp (+1 650-276-7756).

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Clinical Safety Disclaimer: Laser pigmentation and vascular outcomes depend on lesion depth, Fitzpatrick skin phototype, UV exposure habits, and hormonal factors. Temporary effects may include mild erythema, transient edema, temporary darkening or micro-crusting of superficial pigmented lesions, or rare post-inflammatory pigmentary changes. Strict broad-spectrum UV protection and an in-person dermatological diagnosis are required.